Human trafficking is quickly becoming one of the world’s largest criminal industries. Many of its victims are children and adolescents. Traffickers often prey on the vulnerable, promising them a better life. Tactics, such as grooming, coerce victims into prostitution or other forms of human trafficking. This paper reports research on generational changes between Millennials and Generation Z that increase susceptibility to sex trafficking. Based on interviews conducted with school counselors, low personal achievement and poverty may increase a youth’s chance of being sex trafficked. Because of this, career counseling offers a realistic method for achieving self-sufficiency through future job opportunities. This article offers information on sex trafficking and details specific career counseling strategies to prevent youth susceptibility to sex trafficking.